Biomarkers in Sepsis

52-year-old male – Known case of type 2 diabetes mellitus, systemic hypertension, S/P thyroidectomy for multi-nodular goiter – poorly compliant with life style modifications and diabetic medications – presented with 3-day history of high-grade fever associated with chills and rigor – decreased food intake – altered mental status and decreased urine output. His Vitals and investigations are as follows

Heart rate – 116 per minute

Blood pressure – 100/70 mmHg

SPO2 – 89% with 10 L of 02 on NRBM

Temperature – 101 F

Respiratory rate – 28 per minute

GCS – 14/15

Blood investigations and ABG sent

ABG – pH 7.326, PCO2 – 38.6 mmHg, PO2 – 61mmHg, HCO3 – 19.7 mmol/L, BE - -6, Lactate – 4.1 mmol/L

Procalcitonin and CRP have been sent.

Patient has been shifted to your unit for further management